Graduate Research Assistant

Building multi‑scale models of immune cells to decode human immunity.

Dennis Startsev portrait

About

I am a graduate research assistant in the Biochemistry Department at the University of Nebraska–Lincoln. I began my Ph.D. program in 2024 where I explore multi‑scale mathematical modeling of immune cell behavior, integrating metabolic and environmental signals. I earned my B.Sc. in mathematics from the University of Nebraska–Lincoln and was part of the STEM CONNECT Scholarship program throughout my undergraduate years.

Since joining Dr. Tomáš Helikar’s laboratory in mid‑2022, I have been contributing to the ambitious effort to build a digital twin of the human immune system. The project aims to create a comprehensive virtual replica of immunity that could help society become safer and provide tools that inform people of their risk factors. Our iterative approach started by modelling 20–25 key immune cell types and now seeks to scale the system to include every cell and physiological process.